Never - blog by Never

 


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Review of crohn's drugs in testing Private Entry

Posted 08-Sep-2015 at 07:08 AM (07:08) by Never

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A bacteria-sensing receptor, the proteine NOD2 exists in more than 58 varients. 80% of them are linked to crohn's. Another proteine, HSP70 (heat shock proteine 70) is a chaperone protein that helps proteins fold themselves into correct 3-dimentional shapes. If you increase the expression of HSP70, mutant versions of NOD2 found in crohn's were able to sense bacterial cell wall fragments and send the right signal to the immune system.

This from Catherin Leimkuhler Grime,...
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Rating: 3 votes, 5.00 average.

Visit to Duke Lemur Center

Posted 07-Mar-2013 at 08:03 AM (08:03) by Never
Updated 07-Mar-2013 at 08:38 AM (08:38) by Never

"Hey lady, if you want to get your camera ready, I'm going to be cute now" seemed to be what this lemur was thinking as he stretched out to sunbath on a moderately cloudy February day in North Carolina when the sun had broken through the clouds. I obliged him as best I could with my cell phone. We chatted a bit (ok, I chatted, he looked cute) and I got a few good photos. This is a male ringtail lemur.

...
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pz lashes out (again) at a fan

Posted 24-May-2012 at 04:24 AM (04:24) by Never
Updated 30-Mar-2013 at 04:15 AM (04:15) by Never

Once in a while I take a notion to do a random search on Google for the unexpected results. The other night I threw a few search terms in which had little to do with the result I found on, I think it was page 4.

It was a link to pz's blog, Pharyngula, this post by a guest blogger on the topic of Why I'm an Atheist. I notice there is some mention in it of not being able to share their lack of faith with family and their only place to ask question was the internet.

The...
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Rating: 3 votes, 5.00 average.

Dark Shadows fan and fandom

Posted 06-May-2012 at 08:16 PM (20:16) by Never
Updated 06-May-2012 at 08:25 PM (20:25) by Never

Most of us of "a certain age group" ran home from school every day to see each day's episode of the gothic soap opera Dark Shadows on TV which ran in the USA from 1966-1971. I was one of them. After enjoying the original series, the 2 movies - House of Dark Shadows and Night of Dark Shadows, and the 1991 prime-time resurrection, we are about to see a new movie version open next week. Here is some trivia at IMDB in anticipation of the release on May 11th. I'll try to blog about that after seeing...
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Nostalgia

Posted 26-Jun-2011 at 09:17 AM (09:17) by Never

First from dictionary.com:

Nostalgia: a wistful desire to return in thought or in fact to a former time in one's life. Also: a yearning for the return of past circumstances, events, etc.

Reading various phrases, words, links, etc. tonight that certainly cause this feeling.

I think I'll add to this one of my all-time favorite songs because if there's one thing I don't ever do it's give up.

...
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Rating: 3 votes, 5.00 average.

Girls' dress at turn of century

Posted 07-Feb-2011 at 04:31 AM (04:31) by Never
Tags , , , ,

I was going through the piano bench last night - something I'd not done before. Almost everything in it belonged to my (now deceased) grandmother or uncle. I found where a local (to her) newspaper had been stuffed among the music. In it is a section where the writer had interviewed my grandmother asking what children had worn 100 years ago.

The article was from 1989. Grandma was born in 1898. The following was her response. Mind you, she had told these things to me personally many...
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Trans-Allegheny (local) bookstore closed

Posted 24-Oct-2010 at 07:07 PM (19:07) by Never

I missed the news item earlier in the year and had such a busy summer that I hadn't been by the store to know it was closed. I love to get lost in a used bookstore, this one even moreso due to the fascinating building and atmosphere.

It was the former city library, one of many of the Carnegie libraries built earlier in the century. When the library built a new modern building and vacated this one, this was purchased to turn into a used bookstore which is of course a perfect use....
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So I met this dog...

Posted 28-Aug-2010 at 08:31 PM (20:31) by Never

His name is Bruno and he's part of Lifelinking's lovely family.

I've always been a cat person. About 6-7 years ago I also became a bunny person. I've never cared for dogs. A few of them were just tolerable, but most were annoying and some I really couldn't stand. (One I know jumps up off the ground and tries to eat your hair when you're standing).

I declared Bruno to be part cat. He's friendly, likes to lie around on the couch and snuggle up against you. He's...
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My first Pub Quiz (at Discworld)

Posted 27-Aug-2010 at 03:18 AM (03:18) by Never
Updated 27-Aug-2010 at 11:16 AM (11:16) by Never (The answer was 16 - I forgot that fast!!!)

How many toes does a pig have? Apparently it is 16, but many at our table wanted proof. What movie won the first Academy award? Who put out this book or that music album? Most of these were quite challenging, but even more-so to myself (a little lacking in the memory department).

Unfortunately there was no individual award for not getting any of them right. Fortunately there was cheering for the table I was sitting at who won the quiz. Intelligent group from various parts of...
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Brand Name Quality - or Not

Posted 07-May-2010 at 08:15 AM (08:15) by Never

I may as well do my first blog entry on a subject I have some familiarity with. It's all over the news, but I've had people IRL ask me about it so I'm going to talk about the recent recall of McNeil brand OTC medications for children.

It seems that the FDA discovered raw material used in manufacturing these pediatric liquids at a facility in Pennsylvania. Lots made at other manufacturing facilities are still on shelves (though I can't imagine anyone would buy them).

...
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